Introduction to ARA-290
ARA-290 is an engineered variant of the hormone erythropoietin designed to activate innate tissue repair receptors.
It signals through protective pathways in the body while avoiding potential risks from erythropoietin receptor activation.
Medical Uses of ARA-290 Peptide
ARA-290 is being studied for its wide-ranging therapeutic effects on conditions like diabetes, high cholesterol, chronic pain, nerve damage, and wound healing.
- Enhanced Glycemic Control: Studies indicate ARA 290 can significantly improve markers of long-term blood sugar regulation and glycemic control in patients with type 2 diabetes mellitus.
- Pain and Nerve Damage Relief: Multiple human trials found ARA 290 effectively reduces neuropathic pain and nerve fiber deterioration related to sarcoidosis, diabetes, chemotherapy, and other causes. It helps regrow and protect nerve cells.
- Anti-Inflammatory Cardiac Benefits: Experiments using chronic ARA 290 treatment show substantially decreased levels of major inflammatory signaling molecules like TNF-alpha and IL-6 in heart tissue. This exerts protective, anti-inflammatory effects.
Through these and other mechanisms, ARA 290 peptide demonstrates the promising potential for managing diabetes, nerve damage, pain, inflammation, and related conditions.
Diabetes Management
By improving glucose tolerance and insulin function, ARA-290 lowers HbA1c levels in preclinical research by up to 1%.
This indicates its potential to assist in managing high blood sugar and improving diabetes.
Cholesterol Regulation
Animal studies show that ARA-290 enhances lipid metabolism and lowers circulating LDL cholesterol levels by up to 30%.
This cholesterol modulation may support better cardiovascular health.
Pain Relief
Through anti-inflammatory actions and protecting nerve cell function, ARA-290 reduces neuropathic pain signals by over 50% in rodent models.
It also shows promise for pain relief after nerve injury or from diabetes, chemotherapy, etc.
Wound Healing
By spurring tissue repair pathways, ARA-290 accelerates recovery from skin wounds, with >60% faster closure and healing rates per study.
This can aid healing after surgery, burns, ulcers, or other tissue damage.
Typical ARA-290 Dosage
In clinical trials, intravenous ARA-290 doses range from 1.5 to 30 micrograms per 1 kg of body weight.
Dosing frequency spans a single dose up to multiple infusions per week over months.
FAQs About ARA-290
- How is ARA-290 administered?ARA-290 is given intravenously in clinical trials, and subcutaneous injections are also being researched.
- What conditions are ARA-290 used for? The main conditions studied are diabetes, nerve pain, wound healing, and cholesterol/cardiovascular benefits.
- Are there side effects? Few side effects have been reported, but may include headaches, nausea, and rash. More studies are still needed on safety.
Conclusion on ARA-290 Peptide
With broad applications, ARA-290 shows therapeutic promise for diabetes, cholesterol regulation, pain relief, healing, and more.
You can visit our peptides page to learn more about our other peptides.
